Online ISSN: 2187-2988 Print ISSN: 0911-1794
特定非営利活動法人日本小児循環器学会 Japanese Society of Pediatric Cardiology and Cardiac Surgery
Pediatric Cardiology and Cardiac Surgery 33(1): 24-35 (2017)


小児心臓移植患者の遠隔期の管理Long-term Medical Care after Pediatric Heart Transplantation

大阪大学大学院医学系研究科小児科Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan

発行日:2017年1月1日Published: January 1, 2017


Survival after pediatric heart transplantation has been improving ever since the procedure was first performed. The international survival data showed that the actual 5-year survival rate was approximately 70%. This improvement was observed mostly in the period immediately following heart transplantation, but intermediate and late mortality have not improved. Therefore, how to manage pediatric recipients in the long term after heart transplantation is important issue. Not only management of immunosuppressive therapy and rejection but also detection and treatment of major post-transplant complications, including infection, coronary allograft vasculopathy, renal dysfunction and malignancy are essential. In addition, other important issues are to assess somatic growth and intellectual and psychosocial development in children after heart transplantation. Transitional care, including management of nonadherence in adolescents after transplantation, is also important. Total post-transplantation care by a multidisciplinary team may improve long-term outcome after pediatric heart transplantation.

Key words: pediatric heart transplantation; post-transplant follow-up; recipient care; long-term outcome

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