日本小児循環器学会雑誌 Pediatric Cardiology and Cardiac Surgery

Online ISSN: 2187-2988 Print ISSN: 0911-1794
特定非営利活動法人日本小児循環器学会 Japanese Society of Pediatric Cardiology and Cardiac Surgery
〒162-0801東京都新宿区山吹町358-5アカデミーセンター Japanese Society of Pediatric Cardiology and Cardiac Surgery Academy Center, 358-5 Yamabuki-cho, Shinju-ku, Tokyo 162-0801, Japan
Pediatric Cardiology and Cardiac Surgery 36(2): 116-120 (2020)
doi:10.9794/jspccs.36.116

ReviewReview

私が岡山大学から発信した外科手術と治療法Development of Innovative Surgical Treatment from Okayama University

1カリフォルニア大学サンフランシスコ校小児心臓外科教授University California San Francisco ◇ California, USA

2岡山大学心臓血管外科名誉教授Professor Emeritus, Okayama University Graduate, School of Medicine, Dentistry and Pharmaceutical Science ◇ Okayama, Japan

発行日:2020年6月1日Published: June 1, 2020
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私の留学時代の恩師Sir Brian Barratt-Boyes(超低体温停止法を開発,ホモグラフトを世界で最初に大動脈弁置換に使った)は良き心臓外科医であると同時にacademic surgeon, innovative surgeonであれと説いた.もう一人の恩師Roger Meeは,LV training, Double switch手術,TGAに対するTrapdoor法など多くの新しい手術法を次々と開発した.2人の偉人の薫陶を受けて育った私は,自分自身も世界に発信する新しい治療法を考えるようになった.1993年に岡山大学に帰り,多くの複雑心奇形症例の手術症例に恵まれ,多くの成功と同時に多くの命を失った.命を失った症例から多くのことを学び,それが新しい手術法,治療法を生み出す原動力になった.

若い人達も学術的で革新的なマインド(mind)をもち,日本発の新しい手術法,治療法の開発をしてもらいたい.

I became a professor and chairman at the department of cardiovascular surgical unit of Okayama University in 1993, two years after I was back from a consultant cardiac surgeon at Royal Children’s Hospital, Melbourne. Before I started a new program at Okayama University, University Hospital had been doing less than 5 pediatric surgical cases a year. Now, we perform 300–400 pediatric cardiac surgeries per year and has become one of the leading pediatric cardiac surgery hospitals in the world. Since 1993, we have done more than 8,000 pediatric cardiac surgeries with a mortality of around 1% and published more than 300 papers in English. These achievements are contributed to by the influence of my mentors in New Zealand and Australia: Sir Brian Barratt-Boyes at Green Lane Hospital, NZ, who developed homografts and profound hypothermia and circulatory arrest and Roger Mee at the Royal Children’s Hospital, Melbourne, who developed techniques including the trapdoor technique in arterial switch operations, double switch operation for patients with cc-TGA, and the Mee technique for intramural coronary arteries. I have been greatly influenced by these two legends. In 1998, we developed a new surgical technique, the so-called Sano shunt (RV-PA shunt), as the first stage palliation for hypoplastic left heart syndrome (HLHS). Other new procedures include RV/RA exclusion to treat severe forms of Ebstein’s anomaly in 1996, staged biventricular repair of pulmonary atresia and intact ventricular septum in 2001, and cerebral perfusion during aortic arch repair in 1996. More recently we started to research progenitor cell therapy for single ventricle patients with heart failure, which went to Phase I clinical trial in patients with HLHS in 2011. This was the first successful clinical trial of cardiac progenitor cell therapy in a pediatric population. We have now finished Phase I and II, and began Phase III (a multi-center study) in August 2016. My mentors always told me to be an academic and innovative surgeon and this is what I want to share with the next generation.

Key words: surgical Innovations; RV-PA Shunt (Sano procedure); RV/RA Exclusion

This page was created on 2020-05-28T15:36:44.311+09:00
This page was last modified on 2020-06-18T10:10:47.000+09:00


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